An acquaintance of mine buried her daughter yesterday. She died on her 20th birthday of an opioid overdose. She had been in recovery for many months, but had suffered repeated relapses. Her introduction to opioids wasn’t through some backstreet pusher. Her physician gave her a prescription. I’m taking this one particularly hard. I am grateful, however, that Congress seems to be taking this problem seriously. I only wish I could say the same for the Food & Drug Administration.
While only accounting for about 5 percent of the population, the U.S. now consumes 99 percent of the world’s Vicodin and 84 percent of its Oxycontin.
According to the Centers for Disease Control, 12 million people reported using prescription painkillers non-medically in 2010 (meaning without a prescription or only for the feeling), the most recent year for which there is data. Since 1999, the number has led to an over 400 percent increase in female deaths and 265 percent increase in male deaths involving opiates. In 2008, the CDC reported 14,800 deaths from prescription painkillers. Two years later that number had increased to 16,651. Opioid overdose deaths in America are now greater than heroin and cocaine combined.
But prescription opioids are only the beginning of the problem. While the high is similar to that of heroin, pain pills are roughly six times the price. But with opioids status as the second-most addictive substance to tobacco, those who get hooked on prescriptions are likely to search for another way to get high. Which may explain why the number of heroin users nearly doubled from 373,000 people in 2007 to 620,000 in 2011.
After the dirty work of explaining to Sen. Feinstein and cohorts what the drug landscape in America is, Dr. Andrew Kolodny, chief medical officer of nonprofit drug rehabilitation organization Phoenix House, was the first to take the reins. “This epidemic was caused by the medical community,” he said, looking at Feinstein. “We [doctors] were responding to a campaign that encouraged long-term use. Minimized risk and maximized comfort,” he said. Instead of lessons about the dangerous, addictive, and deadly qualities of prescription opioids, he got lessons on relieving pain. The result was the over-prescription and over-consumption of prescription opioids that still exists today—or at least that’s how he sees it. “Most patients with chronic pain on long-term opioids… we’re probably harming them,” he says.
But doctors aren’t the only ones at fault, Kolodny says, even if they are the original purveyors of the drugs. “The CDC is calling for reduced prescribing, especially for chronic pain. But the FDA continues to approve dangerous opioids and continues to allow marketing of opioids for chronic problems like low back pain.” It’s a move that he says turned medicine cabinets into death traps. Without a complete overhaul of the opiate world, he worries it will continue. “Overdose deaths will remain at historically high levels, heroin will continue flooding into our neighborhoods, our families will continue to suffer.”
Somewhere around eight percent of the population is genetically predisposed to react to opioids differently from the rest of us, just as around eight percent of the population reacts differently to alcohol. These are people who have what can be considered a brain disease that only really kicks in when they are exposed to certain substances. Our culture encourages substance abuse, but most kids grow out of it sometime in their twenties. But some kids become addicts and lose the ability to control their use. If you give these kids a prescription for vicodin, there is a very good chance that they won’t stop taking opiods until they are dead. Along the way, they will be transformed into pathological liars and thieves who no longer resemble their former selves except in the most superficial ways. Many people describe it as “losing their soul.”
They can regain their soul by getting treatment and staying sober, but they won’t be happy and content as sober people. They won’t “feel” right. Sometimes, with the help of a 12-step program, miracles do occur and addicts learn to feel normal even when living a sober life, but it takes a real commitment to the program. This can take a lot of time and involve many relapses and overdoses. Overdoses are usually fatal unless there is very prompt medical treatment using a drug called Narcan. For my friend’s daughter, this time, there was no prompt medical treatment.
I’m sorry for the tragic loss for everyone who knew the young woman.
My sincerest condolences to all concerned.
Me too.
Yes, condolences.
On the other hand… I’ve had to watch friends go through severe pain which could have, and should have, been handled by opiods but wasn’t because fucking assholes scared doctors from perscribing them. Those fear mongers deserve to die a very agonizing death screaming and begging to be killed. People do need them.
The problem is the war on drugs. We had the crack problem here and when that left meth came, when meth left heroin came, they got rid of heroin and now we are up to our eyeballs in cocaine.
Ultimately that helps nobody. Decriminalize all of it, allow over the counter codine products, legalize pot completely, and raise taxes to fund addiction clinics that treat addiction as a disease and not a criminal problem. Unless all of those things are done, the situation will not improve.
I know if I was in severe pain I’d want to know that I could be prescribed something that would work. It’s scary to think policies might be enacted that could leave even more folks suffering needlessly.
Meanwhile, here in MN we’re still debating whether to barely legalize medical marijuana, while docs are over prescribing opiates to god knows how many people and the heroine problem gets worse.
What an f-d up world…
I’d be nice to have a heroine problem instead of a heroin problem. I find female heros much more interesting than male heros.
hehe
Usum non tollit abusus …
you revel in being an asshole.
I’d say someone who wants to deny people medicine that works for chronic pain is an asshole. If you want to deny people pain reduction, I have no problem with saying you should be made to suffer as well.
Unfortunately, the opioid problem in my community is so widespread that I am familiar with quite a few stories about how kids got hooked.
I know of one kid who was prescribed them after gall bladder surgery.
One kid who got them from a friend who had his tonsils out.
One kid who had his wisdom teeth out.
One kid whose mother was in a major accident and had diladid always lying about.
The original prescriptions were obviously justified, but either the quantity was absurd or the prescribee didn’t take care to make sure their pills weren’t diverted.
Now, I had four impacted wisdom teeth taken out when I was 15 years old. I was in a lot of pain. I was prescribed fairly strong codeine pills. Today, I might have been given something much stronger and more addictive.
The solution isn’t to just deny people pain medication. It’s to prescribe as little as possible both in terms of the strength and in terms of the pills. And then you have to educate the patient about the risks of addiction. If the pills dull the pain, great. If they make you feel ‘normal’ for the first time in your life, that’s a major alarm bell.
They need to know where to take any left over pills. In my community, there is a bin at the police station. That’s new this year.
Most people can kick pain killers even if they have some nasty withdrawal symptoms. But almost one in ten people will not be able to kick. And they will move on to stronger and stronger opioids, eventually becoming IV users. And, if they can’t afford it, they will go to heroin and they will steal and lie to get it.
So, I don’t envy doctors who handle chronic pain or prescribe painkillers, but they need to be extremely cautious and responsible.
Actually, though he’s being inflammatory in his delivery, dude has a legit point.
What happened to your friend’s daughter, and to Phillip Seymour Hoffman, is a tragic waste. As a physician, I will certainly agree with you that opioids are overused. But I can also tell you that for a lot of chronic, moderate to severe pain, there is no substitute. Not using narcotics in such a circumstance is downright cruel. In fact, almost anyone who has an operation of any kinds needs narcotics for at least a week or two.
I never, ever prescribe narcotics. But then again, I don’t generally deal with chronic pain, and when I do there are alternatives. Not everyone has alternatives. Most physicians are, if anything, too reluctant to prescribe these drugs for fear of getting people hooked.
I don’t see a decent solution to this problem, honestly.
I have an idea. Since the “U.S. now consumes 99 percent of the world’s Vicodin and 84 percent of its Oxycontin,” maybe the problem isn’t people in chronic pain being denied opioids. Maybe, just maybe, the people in the rest of the world, you know, the 95% have an equal amount of chronic pain but nowhere near the same number of dead 20-year olds.
Legalizing medical marijuana might help.
First step towards a solution is to find a diagnostic test to find people with a biochemical predisposition to opioid dependency. IF that is possible … and it may not be for two reasons:
Regarding #2 I note the pharmaceutical companies could stymie outside investigators by claiming Intellectual Property protection.
you have to troll this thread? the classic “ive got mine, f*** y’all”
Disagree. America has a Dealing With Reality problem. Opioid addiction is one example. The first step to recovery is to stop thinking of addiction as a moral “failure” (sic) and to treat it as the medical problem it is.
From the CDC:
And who pays for those drugs (6X more expensive than heroin) that friends and relatives give away or have stolen from them?
I am sorry for the loss of the young woman, Boo, and so many others as well. But a statement like this makes my blood boil:
I’ve had two experimental organ transplants, a stroke, three types of cancer, close to 30 surgeries now, and all the complications that come with not having had a functional immune system for the last two decades. During that same time I’ve created – from scratch – a successful journalism career, and then, when that went the way of the dodo, another new career as a successful political consultant building on years of activism in countless issues. All in all, I think I have a pretty good record of giving back to my community.
None of that – none of that – would have been possible at any point without oxycodone. Nothing else works – we’ve certainly tried. And it does work. Oxycodone has literally made it possible for me to function each day. And that, in turn, is only possible because I have a primary doctor who is more concerned about my quality of life than she is about scaremongering assholes like this.
I’ve also spent any number of nights screaming my fking head off in the ER or ICU from pain, unable to get any relief because some attending doc is afraid I’ll develop an addiction to a drug I’ve been taking successfully for 20 years. This sort of rhetoric does not serve anyone well.
You want to blame pill-pushing doctors? Back up a bit. How many doctors push pills because they aren’t allowed to spend more than ten minutes per patient, and it’s the easiest way to cope with that limitation? How many times is it insurance companies that will pay for a pill, but not, say, a tens unit?
We’ve got a medical system where profitability is a more important measure of whether people will get the health care they need than, oh, I dunno, providing the actual health care people need. We also have a society in which large numbers of people feel the need to self-medicate, and enough wealth to fuel the self-medication. And, of course, we have the War On Drugs, another profit-driven catastrophe that treats a disease as a criminal matter (as well as a moral failing) rather than a health issue.
I get it. None of those things are going to change any time soon, so let’s not talk about them – let’s go the easy route and just leave people in pain. Believe me, there’s plenty of doctors already doing exactly that, out of fear and self-preservation.
On behalf of all the people guys like this would condemn to a lifetime of misery: thanks a lot, asshole.
But, Geov, you aren’t “most patients.”
You may occasionally be the victim of the vigilance of responsible doctors, or the victim of a doctor who doesn’t have the time or the temperament to understand your needs. But oxycodone was basically made for you. It was not made for “most” chronic pain victims.
You can probably take enough oxycodone to kill an addict without it even making you high. That’s because you are in serious pain.
All you need to do is look at the statistics. People across the border from you in Canada also suffer from chronic pain, but they consume far less than 1% of all the hydrocodone produced in the world. They consume far less than 16% of the oxycodone produced in the world.
Why are we Americans vacuuming the stuff up? It’s because doctors and dentists are prescribing this stuff to people who absolutely do not need it. They may want it. It may do the job of killing pain better than alternatives. But a lot of times it’s like using a sledgehammer to hang a picture.
This epidemic is ravishing our country right now, and it’s all because of the doctors and dentists. Period.
They need to stop giving these meds to people at the drop of a hat, and they need to limit how many pills they give out. I don’t want them to swing too far in the other direction and leave people suffering, but we have a long way to go to get to where Europe or Canada is, and they’re in a much better place.
Let’s not ignore some of the obvious reasons (or follow the money).
1) WHO: Direct-to-consumer advertising under fire
Not coincidental that consumption of prescription pain medications increased after advertising bans were lifted in 1985 and regulations significantly eased in 1997. Doesn’t matter that opioids aren’t advertised — the meta-message that we’re bombarded with is “got a problem, get a pill from your or a doctor.”
I was going to describe how opioid use can be life changing (for the better), but you said it better than I.
I am sorry for your loss, BooMan, and for those examples you listed — I am sorry for their families as well.
Reading of your feelings, BooMan, towards pain relief being overprescribed, I have resisted the urge to post as it seems to be a theme lately. It appears that this friend’s situation (and others) have impacted you greatly — as it would anyone.
Please keep in mind that every situation is different. You may come to these feelings from a different place than others. Everyone experiences pain differently, and there is no magical formula to say how much of which medication is appropriate — that is why we have doctors, and why medicine is a science that continues to progress. Hopefully we tailor treatments as best we can — there will always be drug seeking behavior and those predisposed to addiction. On the other hand, we also have chronic pain patients who can only get through the most simple activities with relief from their pain. Furthermore, there are many conditions for which there is neither a cure nor treatments that provide relief — I respectfully submit that your broad strokes regarding opioid prescriptions are not taking everyone’s situation in to consideration.
Doctors, Hospitals, Insurers and most especially the DEA have been way overboard in preventing adequate pain relief for decades. There finally has been some realization of how chronic pain is in fact a whole syndrome in itself. Those that experience “true” (whatever that means; whoever gets to decide) chronic pain have every aspect of their life impacted — as well as those around them. Proper use of opioid medication is appropriate in many situations. It is between the doctor and the patient to work out what is appropriate, in my opinion — not broad strokes undoing what has been gained in the realization of chronic pain’s debilitating effects on the patient as well as their family and ultimately society as a whole.
Again, sorry for your loss’ BooMan. Please keep in mind those that experience chronic pain who are helped by opioids which will be impacted by broad pendulum swings against overdoses. There will be drug seeking behavior, some people will become addicts, and some will overdose. I believe the percentage (although actual lives and tragic) would be lower than you think vs. those who benefit in getting through their daily activities.
Again.
The numbers speak for themselves.
Take any country that is at a similar level of economic development with wide accessibility to both health care and pharmaceuticals, and look at how they treat chronic pain vs. how we treat chronic pain.
We consume 99% of the hydrocodone in the world. Why is that?
Is it because we’re leaving too many people in post-operative agony?
We consume 84% of the oxycodone in the world. Why is that?
Is it because we’re denying too many people treatment for chronic pain?
Of course not.
The numbers speak for themselves.
If you could show me that people in the rest of the world are really suffering in large numbers because they aren’t getting treatment for their pain, then I might have more sympathy for your argument. But you can’t show me that because it simply isn’t happening. Canadians get the same dental work that we do. Swedes have the same kinds of back injuries. But they aren’t treating that pain with opioids except in the most extreme cases.
And, so, they have many fewer dead 20 year old girls.
It’s a complex thing to treat pain effectively, but part of this is very simple. You cannot safely give opioids or any other medication to people when nearly 10% of them will have their lives ruined by it.
With someone like Geov, you have no choice. Most post-operative patients are definitely going to want some opioids, but remember that there are hundreds of thousands of people who can’t take opioids either because their body reacts badly to them or because they are a recovering addict. There are strategies to manage pain for those people. They are less than ideal, but so is burying your child before they can drink legally.
I also don’t want the pendulum to go too far in the other direction. I am not suggesting that doctors refuse to issue pain medication. I am suggesting that they do so very cautiously and that they only give out a few pills at a time and that they educate people about how to know if they may be predisposed to addiction.
Do you seriously think Congress — especially this Congress — can establish any legislation that will effectively deal with this problem? When they can’t even take marijuana off the scheduling list (let alone reschedule it), and when we have the DEA sweating bullets that the entire jobs are on the line when the Drug War comes crashing down? They’re definitely looking at a new excuse to fund their (mostly) useless budget. This seems like just the ticket.
In the end it comes down to if you think this is a problem, and it’s a problem that can be solved legislatively, what do you propose we do about it?
First of all, in the comment you are responding to, I did not mention one law or any proposed laws or regulations.
However, in the body of the post I did mention Congress and say that I am glad that they are looking at the problem.
The first thing they can do is to overrule the FDA and ban fucking Zyhydro. If someone needs that, they can get it special order or something from a pharmacist who knows how to cook. Fuck no to mass production.
Then they can get serious about treatment and oversight of treatment. There is a whole economy now that has evolved to deal with and take advantage of addicts. Florida is half people who don’t know how to vote and half people running disreputable halfway houses and rehabs. I guess there is a third half dedicated to Medicare fraud.
As for interdiction, it isn’t particularly effective, but it can be done on the prescription side by making sure pills can’t be snorted and other methods like lacing them with Tylenol (as is done with Vicodin).
There’s a lot that Congress can do, and do effectively. There’s a lot the administration can do through education and regulation.
Right I know you didn’t, but in the original post you did mention Congress in the affirmative as for them to do something.
The reason I asked with respect to this is because you seem to think other countries are doing something different. Are they? If so, what are they doing? Are they following the prescriptions you just laid out? I know they usually allow drugs on the market sooner than the FDA.
Start with this:
I mean, what in the fuck?
The idea is that we need this for chronic pain because you can’t feed people the tylenol in vicodin round the clock or their livers will quit.
So, give them oxycodone then. We already killed enough people with that. It works very well for the people who actually need it. Why introduce another killer when it is not necessary?
I think it is important to separate the problems.
Drugs like Oxycodone were developed and approved for chronic pain – that pain that isn’t likely to go away and for which there is no other treatment. On balance, dependency and addiction is a rational trade off. That is not a problem.
Marketing it heavily for other types of pain, as it was, to doctors who may not have adaquate training in pain management and addiction, as many fit the bill, was predicted 15 years ago to create the opiate epidemic we have now. That’s a problem and from first hand observation I’d say the pharmas don’t care much about it.
Putting someone on any opiate for more than four weeks is now known to create dependency. Many people receive prescriptions for more than that. Many people sense their dependency and get off them. Others keep taking them either because they are atill in pain or because they think it is ok under a doctors care, or because they find confronting the dependency is too difficult. Before too much longer it can become a full blown addiction and it is off to the races. Medical professionals for many reasons may not know how and/or be motivated to manage that risk proactively. That is a different problem.
That is all correct.
And, I might add, there are two kinds of opioid addicts.
If you give anyone an opioid for long enough, they will be addicted to it and suffer from withdrawal symptoms when they attempt to quit.
There is a subset of people, however, who react to opioids in an unusual manner. Rather than making them feel sick and woozy, they make them feel “normal.” Where they had been constantly anxious and restless, they are suddenly comfortable in their own skin for the first time. It’s a psychological godsend to them.
So, this subset of addict is immediately attracted to the psychological effects of the drug. They will seek more out to maintain this newfound feeling of “rightness.”
This is the group for whom it is too dangerous to prescribe opioids. Kicking the habit is hard for anyone, but it is very very hard for the folks for whom it is serving as a mood modulator. They will crave the drug long after they have detoxed.
Now, estimates are that this group is around 8% or so of the population. As a group, they are prone to seek out drugs for recreational purposes specifically because they are not comfortable with themselves and sobriety is a burden to them. There are ways to screen for them both before prescribing and once they have starting taking the drug.
Indicators might be depression, anxiety, social isolation, drug use, expressions of alienation, and so forth.
Patients could also be instructed about what to look for in their reaction to the drug. Does it make them feel sick and groggy or does it feel fantastic and like a giant weight has been lifted off their shoulders? If the latter, they like the drug too much and cannot take it without great risk of dependency.
Ordinarily, we would never allow a drug to be prescribed if there was an 8% chance that it would turn the patient into a full-blown junkie. But pain is pain. It must be mitigated somehow. Having said that, opioids are simply not safe drugs.
Another weird feature of opioids is that they don’t really make you high if you are in genuine physical pain. You can take incredible doses of them without fear of overdosing provided that you are in great pain. But if you not in physical pain, the effect is to begin to slowly shut your body down until you eventually forget to breath.
The tolerance also fluctuates dangerously. A recreational user can build up a huge tolerance, but a week in detox will remove it almost totally, leading to immediate overdoses if the addict resumes anything approximately their previous doses.
That’s why most fatal overdoses hit people who relapse after detox or rehab. They think that taking a quarter of their usual dose is prudent, but it turns out to be fatal.
I don’t exactly what happened with this girl. It was her birthday, so maybe she wanted to celebrate. She hadn’t been using for a month or more. It could have been taking too much or it could have been laced with Fentanyl. That’s been going around, although not so much in the eastern part of the state.
http://www.youtube.com/watch?v=2ma_Ouv74_8
RIP